MTR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with MTR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with MTR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with MTR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MTR Down.

Results found

Linked to

	Label	Description
	UQCRB Gene (Entity type)	ENSG00000156467 - ubiquinol-cytochrome c reductase binding protein
	C2 Gene (Entity type)	ENSG00000166278 - complement C2
	RPL36AL Gene (Entity type)	ENSG00000165502 - ribosomal protein L36a like
	ELOB Gene (Entity type)	ENSG00000103363 - elongin B
	WWOX Gene (Entity type)	ENSG00000186153 - WW domain containing oxidoreductase
	SEC63 Gene (Entity type)	ENSG00000025796 - SEC63 protein translocation regulator
	RER1 Gene (Entity type)	ENSG00000157916 - retention in endoplasmic reticulum sorting receptor 1
	CLEC4A Gene (Entity type)	ENSG00000111729 - C-type lectin domain family 4 member A
	EPHX3 Gene (Entity type)	ENSG00000105131 - epoxide hydrolase 3
	VKORC1 Gene (Entity type)	ENSG00000167397 - vitamin K epoxide reductase complex subunit 1

UQCRB

Gene (Entity type)

ENSG00000156467 - ubiquinol-cytochrome c reductase binding protein

Gene (Entity type)

ENSG00000166278 - complement C2

RPL36AL

Gene (Entity type)

ENSG00000165502 - ribosomal protein L36a like

ELOB

Gene (Entity type)

ENSG00000103363 - elongin B

WWOX

Gene (Entity type)

ENSG00000186153 - WW domain containing oxidoreductase

SEC63

Gene (Entity type)

ENSG00000025796 - SEC63 protein translocation regulator

RER1

Gene (Entity type)

ENSG00000157916 - retention in endoplasmic reticulum sorting receptor 1

CLEC4A

Gene (Entity type)

ENSG00000111729 - C-type lectin domain family 4 member A

EPHX3

Gene (Entity type)

ENSG00000105131 - epoxide hydrolase 3

VKORC1

Gene (Entity type)

ENSG00000167397 - vitamin K epoxide reductase complex subunit 1

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.