PLAUR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PLAUR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PLAUR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PLAUR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLAUR Down.

Results found

Linked to

	Label	Description
	EIF3K Gene (Entity type)	ENSG00000178982 - eukaryotic translation initiation factor 3 subunit K
	SMURF1 Gene (Entity type)	ENSG00000198742 - SMAD specific E3 ubiquitin protein ligase 1
	PRRC1 Gene (Entity type)	ENSG00000164244 - proline rich coiled-coil 1
	MRPS12 Gene (Entity type)	ENSG00000128626 - mitochondrial ribosomal protein S12
	MT3 Gene (Entity type)	ENSG00000087250 - metallothionein 3
	SV2B Gene (Entity type)	ENSG00000185518 - synaptic vesicle glycoprotein 2B
	SIKE1 Gene (Entity type)	ENSG00000052723 - suppressor of IKBKE 1
	TIE1 Gene (Entity type)	ENSG00000066056 - tyrosine kinase with immunoglobulin like and EGF like domains 1
	ELOB Gene (Entity type)	ENSG00000103363 - elongin B
	PSMD8 Gene (Entity type)	ENSG00000099341 - proteasome 26S subunit, non-ATPase 8

EIF3K

Gene (Entity type)

ENSG00000178982 - eukaryotic translation initiation factor 3 subunit K

SMURF1

Gene (Entity type)

ENSG00000198742 - SMAD specific E3 ubiquitin protein ligase 1

PRRC1

Gene (Entity type)

ENSG00000164244 - proline rich coiled-coil 1

MRPS12

Gene (Entity type)

ENSG00000128626 - mitochondrial ribosomal protein S12

MT3

Gene (Entity type)

ENSG00000087250 - metallothionein 3

SV2B

Gene (Entity type)

ENSG00000185518 - synaptic vesicle glycoprotein 2B

SIKE1

Gene (Entity type)

ENSG00000052723 - suppressor of IKBKE 1

TIE1

Gene (Entity type)

ENSG00000066056 - tyrosine kinase with immunoglobulin like and EGF like domains 1

ELOB

Gene (Entity type)

ENSG00000103363 - elongin B

PSMD8

Gene (Entity type)

ENSG00000099341 - proteasome 26S subunit, non-ATPase 8

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.