GSE179235 MEK NRAS inhibition 4 v 6 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE179235_MEK_NRAS inhibition_4_v_6_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE179235_MEK_NRAS inhibition_4_v_6_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE179235_MEK_NRAS inhibition_4_v_6_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE179235_MEK_NRAS inhibition_4_v_6_human_dn.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	HDAC2 Gene (Entity type)	ENSG00000196591 - histone deacetylase 2
	DFFA Gene (Entity type)	ENSG00000160049 - DNA fragmentation factor subunit alpha
	EIF4E Gene (Entity type)	ENSG00000151247 - eukaryotic translation initiation factor 4E
	FURIN Gene (Entity type)	ENSG00000140564 - furin, paired basic amino acid cleaving enzyme
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	S1PR3 Gene (Entity type)	ENSG00000213694 - sphingosine-1-phosphate receptor 3
	RBCK1 Gene (Entity type)	ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1
	IL11 Gene (Entity type)	ENSG00000095752 - interleukin 11
	POLR3K Gene (Entity type)	ENSG00000161980 - RNA polymerase III subunit K

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

HDAC2

Gene (Entity type)

ENSG00000196591 - histone deacetylase 2

DFFA

Gene (Entity type)

ENSG00000160049 - DNA fragmentation factor subunit alpha

EIF4E

Gene (Entity type)

ENSG00000151247 - eukaryotic translation initiation factor 4E

FURIN

Gene (Entity type)

ENSG00000140564 - furin, paired basic amino acid cleaving enzyme

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

S1PR3

Gene (Entity type)

ENSG00000213694 - sphingosine-1-phosphate receptor 3

RBCK1

Gene (Entity type)

ENSG00000125826 - RANBP2-type and C3HC4-type zinc finger containing 1

IL11

Gene (Entity type)

ENSG00000095752 - interleukin 11

POLR3K

Gene (Entity type)

ENSG00000161980 - RNA polymerase III subunit K

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.