OPTN Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with OPTN Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with OPTN Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with OPTN Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with OPTN Up.

Results found

Linked to

	Label	Description
	C2 Gene (Entity type)	ENSG00000166278 - complement C2
	HS3ST3A1 Gene (Entity type)	ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1
	RASIP1 Gene (Entity type)	ENSG00000105538 - Ras interacting protein 1
	NXT1 Gene (Entity type)	ENSG00000132661 - nuclear transport factor 2 like export factor 1
	CTSF Gene (Entity type)	ENSG00000174080 - cathepsin F
	INTS6 Gene (Entity type)	ENSG00000102786 - integrator complex subunit 6
	ZNF266 Gene (Entity type)	ENSG00000174652 - zinc finger protein 266
	FBXO28 Gene (Entity type)	ENSG00000143756 - F-box protein 28
	PRP4K Gene (Entity type)	ENSG00000112739 - pre-mRNA processing factor kinase PRP4K
	RPL10A Gene (Entity type)	ENSG00000198755 - ribosomal protein L10a

Gene (Entity type)

ENSG00000166278 - complement C2

HS3ST3A1

Gene (Entity type)

ENSG00000153976 - heparan sulfate-glucosamine 3-sulfotransferase 3A1

RASIP1

Gene (Entity type)

ENSG00000105538 - Ras interacting protein 1

NXT1

Gene (Entity type)

ENSG00000132661 - nuclear transport factor 2 like export factor 1

CTSF

Gene (Entity type)

ENSG00000174080 - cathepsin F

INTS6

Gene (Entity type)

ENSG00000102786 - integrator complex subunit 6

ZNF266

Gene (Entity type)

ENSG00000174652 - zinc finger protein 266

FBXO28

Gene (Entity type)

ENSG00000143756 - F-box protein 28

PRP4K

Gene (Entity type)

ENSG00000112739 - pre-mRNA processing factor kinase PRP4K

RPL10A

Gene (Entity type)

ENSG00000198755 - ribosomal protein L10a

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.