GSE179235 MEK NRAS inhibition 5 v 1 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE179235_MEK_NRAS inhibition_5_v_1_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE179235_MEK_NRAS inhibition_5_v_1_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE179235_MEK_NRAS inhibition_5_v_1_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE179235_MEK_NRAS inhibition_5_v_1_human_up.

Results found

Linked to

	Label	Description
	MEGF9 Gene (Entity type)	ENSG00000106780 - multiple EGF like domains 9
	UQCR11 Gene (Entity type)	ENSG00000127540 - ubiquinol-cytochrome c reductase, complex III subunit XI
	RAB7A Gene (Entity type)	ENSG00000075785 - RAB7A, member RAS oncogene family
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma
	AGPAT3 Gene (Entity type)	ENSG00000160216 - 1-acylglycerol-3-phosphate O-acyltransferase 3
	CYB5R3 Gene (Entity type)	ENSG00000100243 - cytochrome b5 reductase 3
	MED28 Gene (Entity type)	ENSG00000118579 - mediator complex subunit 28
	ATP5MC3 Gene (Entity type)	ENSG00000154518 - ATP synthase membrane subunit c locus 3
	UVRAG Gene (Entity type)	ENSG00000198382 - UV radiation resistance associated
	AFF3 Gene (Entity type)	ENSG00000144218 - ALF transcription elongation factor 3

MEGF9

Gene (Entity type)

ENSG00000106780 - multiple EGF like domains 9

UQCR11

Gene (Entity type)

ENSG00000127540 - ubiquinol-cytochrome c reductase, complex III subunit XI

RAB7A

Gene (Entity type)

ENSG00000075785 - RAB7A, member RAS oncogene family

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

AGPAT3

Gene (Entity type)

ENSG00000160216 - 1-acylglycerol-3-phosphate O-acyltransferase 3

CYB5R3

Gene (Entity type)

ENSG00000100243 - cytochrome b5 reductase 3

MED28

Gene (Entity type)

ENSG00000118579 - mediator complex subunit 28

ATP5MC3

Gene (Entity type)

ENSG00000154518 - ATP synthase membrane subunit c locus 3

UVRAG

Gene (Entity type)

ENSG00000198382 - UV radiation resistance associated

AFF3

Gene (Entity type)

ENSG00000144218 - ALF transcription elongation factor 3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.