OPTN Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with OPTN Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with OPTN Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with OPTN Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with OPTN Down.

Results found

Linked to

	Label	Description
	CCNC Gene (Entity type)	ENSG00000112237 - cyclin C
	IGSF1 Gene (Entity type)	ENSG00000147255 - immunoglobulin superfamily member 1
	ARHGAP44 Gene (Entity type)	ENSG00000006740 - Rho GTPase activating protein 44
	NR3C2 Gene (Entity type)	ENSG00000151623 - nuclear receptor subfamily 3 group C member 2
	TG Gene (Entity type)	ENSG00000042832 - thyroglobulin
	SV2C Gene (Entity type)	ENSG00000122012 - synaptic vesicle glycoprotein 2C
	IQCK Gene (Entity type)	ENSG00000174628 - IQ motif containing K
	PRPH Gene (Entity type)	ENSG00000135406 - peripherin
	ZBTB43 Gene (Entity type)	ENSG00000169155 - zinc finger and BTB domain containing 43
	SHOC2 Gene (Entity type)	ENSG00000108061 - SHOC2 leucine rich repeat scaffold protein

CCNC

Gene (Entity type)

ENSG00000112237 - cyclin C

IGSF1

Gene (Entity type)

ENSG00000147255 - immunoglobulin superfamily member 1

ARHGAP44

Gene (Entity type)

ENSG00000006740 - Rho GTPase activating protein 44

NR3C2

Gene (Entity type)

ENSG00000151623 - nuclear receptor subfamily 3 group C member 2

Gene (Entity type)

ENSG00000042832 - thyroglobulin

SV2C

Gene (Entity type)

ENSG00000122012 - synaptic vesicle glycoprotein 2C

IQCK

Gene (Entity type)

ENSG00000174628 - IQ motif containing K

PRPH

Gene (Entity type)

ENSG00000135406 - peripherin

ZBTB43

Gene (Entity type)

ENSG00000169155 - zinc finger and BTB domain containing 43

SHOC2

Gene (Entity type)

ENSG00000108061 - SHOC2 leucine rich repeat scaffold protein

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.