RFK Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with RFK Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with RFK Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with RFK Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with RFK Up.

Results found

Linked to

	Label	Description
	WDHD1 Gene (Entity type)	ENSG00000198554 - WD repeat and HMG-box DNA binding protein 1
	SF1 Gene (Entity type)	ENSG00000168066 - splicing factor 1
	STAG3 Gene (Entity type)	ENSG00000066923 - STAG3 cohesin complex component
	EHHADH Gene (Entity type)	ENSG00000113790 - enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
	SMC6 Gene (Entity type)	ENSG00000163029 - structural maintenance of chromosomes 6
	ZMIZ2 Gene (Entity type)	ENSG00000122515 - zinc finger MIZ-type containing 2
	GBA3 Gene (Entity type)	ENSG00000249948 - glucosylceramidase beta 3 (gene/pseudogene)
	SIRT5 Gene (Entity type)	ENSG00000124523 - sirtuin 5
	ALG6 Gene (Entity type)	ENSG00000088035 - ALG6 alpha-1,3-glucosyltransferase
	ARIH1 Gene (Entity type)	ENSG00000166233 - ariadne RBR E3 ubiquitin protein ligase 1

WDHD1

Gene (Entity type)

ENSG00000198554 - WD repeat and HMG-box DNA binding protein 1

SF1

Gene (Entity type)

ENSG00000168066 - splicing factor 1

STAG3

Gene (Entity type)

ENSG00000066923 - STAG3 cohesin complex component

EHHADH

Gene (Entity type)

ENSG00000113790 - enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

SMC6

Gene (Entity type)

ENSG00000163029 - structural maintenance of chromosomes 6

ZMIZ2

Gene (Entity type)

ENSG00000122515 - zinc finger MIZ-type containing 2

GBA3

Gene (Entity type)

ENSG00000249948 - glucosylceramidase beta 3 (gene/pseudogene)

SIRT5

Gene (Entity type)

ENSG00000124523 - sirtuin 5

ALG6

Gene (Entity type)

ENSG00000088035 - ALG6 alpha-1,3-glucosyltransferase

ARIH1

Gene (Entity type)

ENSG00000166233 - ariadne RBR E3 ubiquitin protein ligase 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.