IRF2 Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with IRF2 Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with IRF2 Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with IRF2 Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with IRF2 Up.

Results found

Linked to

	Label	Description
	MGMT Gene (Entity type)	ENSG00000170430 - O-6-methylguanine-DNA methyltransferase
	VPS4B Gene (Entity type)	ENSG00000119541 - vacuolar protein sorting 4 homolog B
	SLIRP Gene (Entity type)	ENSG00000119705 - SRA stem-loop interacting RNA binding protein
	ABHD5 Gene (Entity type)	ENSG00000011198 - abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
	ATP2C2 Gene (Entity type)	ENSG00000064270 - ATPase secretory pathway Ca2+ transporting 2
	ZNF611 Gene (Entity type)	ENSG00000213020 - zinc finger protein 611
	VPREB1 Gene (Entity type)	ENSG00000169575 - V-set pre-B cell surrogate light chain 1
	CLDN5 Gene (Entity type)	ENSG00000184113 - claudin 5
	RIMBP2 Gene (Entity type)	ENSG00000060709 - RIMS binding protein 2
	COX5A Gene (Entity type)	ENSG00000178741 - cytochrome c oxidase subunit 5A

MGMT

Gene (Entity type)

ENSG00000170430 - O-6-methylguanine-DNA methyltransferase

VPS4B

Gene (Entity type)

ENSG00000119541 - vacuolar protein sorting 4 homolog B

SLIRP

Gene (Entity type)

ENSG00000119705 - SRA stem-loop interacting RNA binding protein

ABHD5

Gene (Entity type)

ENSG00000011198 - abhydrolase domain containing 5, lysophosphatidic acid acyltransferase

ATP2C2

Gene (Entity type)

ENSG00000064270 - ATPase secretory pathway Ca2+ transporting 2

ZNF611

Gene (Entity type)

ENSG00000213020 - zinc finger protein 611

VPREB1

Gene (Entity type)

ENSG00000169575 - V-set pre-B cell surrogate light chain 1

CLDN5

Gene (Entity type)

ENSG00000184113 - claudin 5

RIMBP2

Gene (Entity type)

ENSG00000060709 - RIMS binding protein 2

COX5A

Gene (Entity type)

ENSG00000178741 - cytochrome c oxidase subunit 5A

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.