GSE145285 PRMT5 p53 inhibition RNA Messenger 0 v 1 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE145285_PRMT5_p53 inhibition_RNA Messenger_0_v_1_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE145285_PRMT5_p53 inhibition_RNA Messenger_0_v_1_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE145285_PRMT5_p53 inhibition_RNA Messenger_0_v_1_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE145285_PRMT5_p53 inhibition_RNA Messenger_0_v_1_human_dn.

Results found

Linked to

	Label	Description
	RPS6 Gene (Entity type)	ENSG00000137154 - ribosomal protein S6
	AKR1A1 Gene (Entity type)	ENSG00000117448 - aldo-keto reductase family 1 member A1
	DFFA Gene (Entity type)	ENSG00000160049 - DNA fragmentation factor subunit alpha
	MLH1 Gene (Entity type)	ENSG00000076242 - mutL homolog 1
	NDUFB1 Gene (Entity type)	ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1
	PSMG1 Gene (Entity type)	ENSG00000183527 - proteasome assembly chaperone 1
	POLR3K Gene (Entity type)	ENSG00000161980 - RNA polymerase III subunit K
	POLA2 Gene (Entity type)	ENSG00000014138 - DNA polymerase alpha 2, accessory subunit
	SMC3 Gene (Entity type)	ENSG00000108055 - structural maintenance of chromosomes 3
	NRBF2 Gene (Entity type)	ENSG00000148572 - nuclear receptor binding factor 2

RPS6

Gene (Entity type)

ENSG00000137154 - ribosomal protein S6

AKR1A1

Gene (Entity type)

ENSG00000117448 - aldo-keto reductase family 1 member A1

DFFA

Gene (Entity type)

ENSG00000160049 - DNA fragmentation factor subunit alpha

MLH1

Gene (Entity type)

ENSG00000076242 - mutL homolog 1

NDUFB1

Gene (Entity type)

ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1

PSMG1

Gene (Entity type)

ENSG00000183527 - proteasome assembly chaperone 1

POLR3K

Gene (Entity type)

ENSG00000161980 - RNA polymerase III subunit K

POLA2

Gene (Entity type)

ENSG00000014138 - DNA polymerase alpha 2, accessory subunit

SMC3

Gene (Entity type)

ENSG00000108055 - structural maintenance of chromosomes 3

NRBF2

Gene (Entity type)

ENSG00000148572 - nuclear receptor binding factor 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.