GSE222676 ABCA1 knockout IMR-90 1 v 0 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE222676_ABCA1 knockout_IMR-90_1_v_0_human_dn.

Results found

Linked to

	Label	Description
	HDAC2 Gene (Entity type)	ENSG00000196591 - histone deacetylase 2
	EIF4E Gene (Entity type)	ENSG00000151247 - eukaryotic translation initiation factor 4E
	IL11 Gene (Entity type)	ENSG00000095752 - interleukin 11
	PSMG1 Gene (Entity type)	ENSG00000183527 - proteasome assembly chaperone 1
	TRIM24 Gene (Entity type)	ENSG00000122779 - tripartite motif containing 24
	POLA2 Gene (Entity type)	ENSG00000014138 - DNA polymerase alpha 2, accessory subunit
	TLE3 Gene (Entity type)	ENSG00000140332 - TLE family member 3, transcriptional corepressor
	SMC3 Gene (Entity type)	ENSG00000108055 - structural maintenance of chromosomes 3
	UBTF Gene (Entity type)	ENSG00000108312 - upstream binding transcription factor
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

HDAC2

Gene (Entity type)

ENSG00000196591 - histone deacetylase 2

EIF4E

Gene (Entity type)

ENSG00000151247 - eukaryotic translation initiation factor 4E

IL11

Gene (Entity type)

ENSG00000095752 - interleukin 11

PSMG1

Gene (Entity type)

ENSG00000183527 - proteasome assembly chaperone 1

TRIM24

Gene (Entity type)

ENSG00000122779 - tripartite motif containing 24

POLA2

Gene (Entity type)

ENSG00000014138 - DNA polymerase alpha 2, accessory subunit

TLE3

Gene (Entity type)

ENSG00000140332 - TLE family member 3, transcriptional corepressor

SMC3

Gene (Entity type)

ENSG00000108055 - structural maintenance of chromosomes 3

UBTF

Gene (Entity type)

ENSG00000108312 - upstream binding transcription factor

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.