GSE212057 SIRT6 overexpression 2 v 1 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE212057_SIRT6 overexpression_2_v_1_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE212057_SIRT6 overexpression_2_v_1_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE212057_SIRT6 overexpression_2_v_1_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE212057_SIRT6 overexpression_2_v_1_human_up.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	PSEN1 Gene (Entity type)	ENSG00000080815 - presenilin 1
	TERF2IP Gene (Entity type)	ENSG00000166848 - TERF2 interacting protein
	ARCN1 Gene (Entity type)	ENSG00000095139 - archain 1 coat protein complex I subunit delta
	MDC1 Gene (Entity type)	ENSG00000137337 - mediator of DNA damage checkpoint 1
	CTNNBIP1 Gene (Entity type)	ENSG00000178585 - catenin beta interacting protein 1
	KLC1 Gene (Entity type)	ENSG00000126214 - kinesin light chain 1
	TRHDE Gene (Entity type)	ENSG00000072657 - thyrotropin releasing hormone degrading enzyme
	DRAP1 Gene (Entity type)	ENSG00000175550 - DR1 associated protein 1
	CUL7 Gene (Entity type)	ENSG00000044090 - cullin 7

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

PSEN1

Gene (Entity type)

ENSG00000080815 - presenilin 1

TERF2IP

Gene (Entity type)

ENSG00000166848 - TERF2 interacting protein

ARCN1

Gene (Entity type)

ENSG00000095139 - archain 1 coat protein complex I subunit delta

MDC1

Gene (Entity type)

ENSG00000137337 - mediator of DNA damage checkpoint 1

CTNNBIP1

Gene (Entity type)

ENSG00000178585 - catenin beta interacting protein 1

KLC1

Gene (Entity type)

ENSG00000126214 - kinesin light chain 1

TRHDE

Gene (Entity type)

ENSG00000072657 - thyrotropin releasing hormone degrading enzyme

DRAP1

Gene (Entity type)

ENSG00000175550 - DR1 associated protein 1

CUL7

Gene (Entity type)

ENSG00000044090 - cullin 7

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.