POLE3 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with POLE3 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with POLE3 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with POLE3 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with POLE3 Down.

Results found

Linked to

	Label	Description
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	NDUFB1 Gene (Entity type)	ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1
	MCCC1 Gene (Entity type)	ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1
	BMPR1A Gene (Entity type)	ENSG00000107779 - bone morphogenetic protein receptor type 1A
	GTF2H3 Gene (Entity type)	ENSG00000111358 - general transcription factor IIH subunit 3
	BRD3 Gene (Entity type)	ENSG00000169925 - bromodomain containing 3
	DIP2A Gene (Entity type)	ENSG00000160305 - DIP2 acetate--CoA ligase A
	LZTS1 Gene (Entity type)	ENSG00000061337 - leucine zipper tumor suppressor 1
	DCAF7 Gene (Entity type)	ENSG00000136485 - DDB1 and CUL4 associated factor 7
	LRRC37A3 Gene (Entity type)	ENSG00000176809 - leucine rich repeat containing 37 member A3

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

NDUFB1

Gene (Entity type)

ENSG00000183648 - NADH:ubiquinone oxidoreductase subunit B1

MCCC1

Gene (Entity type)

ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

BMPR1A

Gene (Entity type)

ENSG00000107779 - bone morphogenetic protein receptor type 1A

GTF2H3

Gene (Entity type)

ENSG00000111358 - general transcription factor IIH subunit 3

BRD3

Gene (Entity type)

ENSG00000169925 - bromodomain containing 3

DIP2A

Gene (Entity type)

ENSG00000160305 - DIP2 acetate--CoA ligase A

LZTS1

Gene (Entity type)

ENSG00000061337 - leucine zipper tumor suppressor 1

DCAF7

Gene (Entity type)

ENSG00000136485 - DDB1 and CUL4 associated factor 7

LRRC37A3

Gene (Entity type)

ENSG00000176809 - leucine rich repeat containing 37 member A3

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.