GSE215461 0 V 1 TOPOTECAN HUMAN DN (Gene Set)

Dcc Asset:

RummaGEO DrugPerturbations 2025.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE215461 0 V 1 TOPOTECAN HUMAN DN.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE215461 0 V 1 TOPOTECAN HUMAN DN.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE215461 0 V 1 TOPOTECAN HUMAN DN.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE215461 0 V 1 TOPOTECAN HUMAN DN.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	BRAF Gene (Entity type)	ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	CDC123 Gene (Entity type)	ENSG00000151465 - cell division cycle 123
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma
	TGFBR1 Gene (Entity type)	ENSG00000106799 - transforming growth factor beta receptor 1
	SIK3 Gene (Entity type)	ENSG00000160584 - SIK family kinase 3
	CA3 Gene (Entity type)	ENSG00000164879 - carbonic anhydrase 3
	SLC6A9 Gene (Entity type)	ENSG00000196517 - solute carrier family 6 member 9

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

BRAF

Gene (Entity type)

ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

CDC123

Gene (Entity type)

ENSG00000151465 - cell division cycle 123

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

TGFBR1

Gene (Entity type)

ENSG00000106799 - transforming growth factor beta receptor 1

SIK3

Gene (Entity type)

ENSG00000160584 - SIK family kinase 3

CA3

Gene (Entity type)

ENSG00000164879 - carbonic anhydrase 3

SLC6A9

Gene (Entity type)

ENSG00000196517 - solute carrier family 6 member 9

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.