SPDEF Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with SPDEF Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with SPDEF Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with SPDEF Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SPDEF Down.

Results found

Linked to

	Label	Description
	OXSR1 Gene (Entity type)	ENSG00000172939 - oxidative stress responsive kinase 1
	CHMP2A Gene (Entity type)	ENSG00000130724 - charged multivesicular body protein 2A
	NCK2 Gene (Entity type)	ENSG00000071051 - NCK adaptor protein 2
	NDUFA6 Gene (Entity type)	ENSG00000184983 - NADH:ubiquinone oxidoreductase subunit A6
	RHEB Gene (Entity type)	ENSG00000106615 - Ras homolog, mTORC1 binding
	RSRC2 Gene (Entity type)	ENSG00000111011 - arginine and serine rich coiled-coil 2
	SERF2 Gene (Entity type)	ENSG00000140264 - small EDRK-rich factor 2
	ELOB Gene (Entity type)	ENSG00000103363 - elongin B
	SRSF10 Gene (Entity type)	ENSG00000188529 - serine and arginine rich splicing factor 10
	TM4SF20 Gene (Entity type)	ENSG00000168955 - transmembrane 4 L six family member 20

OXSR1

Gene (Entity type)

ENSG00000172939 - oxidative stress responsive kinase 1

CHMP2A

Gene (Entity type)

ENSG00000130724 - charged multivesicular body protein 2A

NCK2

Gene (Entity type)

ENSG00000071051 - NCK adaptor protein 2

NDUFA6

Gene (Entity type)

ENSG00000184983 - NADH:ubiquinone oxidoreductase subunit A6

RHEB

Gene (Entity type)

ENSG00000106615 - Ras homolog, mTORC1 binding

RSRC2

Gene (Entity type)

ENSG00000111011 - arginine and serine rich coiled-coil 2

SERF2

Gene (Entity type)

ENSG00000140264 - small EDRK-rich factor 2

ELOB

Gene (Entity type)

ENSG00000103363 - elongin B

SRSF10

Gene (Entity type)

ENSG00000188529 - serine and arginine rich splicing factor 10

TM4SF20

Gene (Entity type)

ENSG00000168955 - transmembrane 4 L six family member 20

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.