LGR5 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with LGR5 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with LGR5 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with LGR5 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with LGR5 Down.

Results found

Linked to

	Label	Description
	HDAC2 Gene (Entity type)	ENSG00000196591 - histone deacetylase 2
	PPP1CC Gene (Entity type)	ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma
	MACROD1 Gene (Entity type)	ENSG00000133315 - mono-ADP ribosylhydrolase 1
	CCR5 Gene (Entity type)	ENSG00000160791 - C-C motif chemokine receptor 5
	UGT2A3 Gene (Entity type)	ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3
	MNS1 Gene (Entity type)	ENSG00000138587 - meiosis specific nuclear structural 1
	NSL1 Gene (Entity type)	ENSG00000117697 - NSL1 component of MIS12 kinetochore complex
	ATF1 Gene (Entity type)	ENSG00000123268 - activating transcription factor 1
	CENPM Gene (Entity type)	ENSG00000100162 - centromere protein M
	MAN1A2 Gene (Entity type)	ENSG00000198162 - mannosidase alpha class 1A member 2

HDAC2

Gene (Entity type)

ENSG00000196591 - histone deacetylase 2

PPP1CC

Gene (Entity type)

ENSG00000186298 - protein phosphatase 1 catalytic subunit gamma

MACROD1

Gene (Entity type)

ENSG00000133315 - mono-ADP ribosylhydrolase 1

CCR5

Gene (Entity type)

ENSG00000160791 - C-C motif chemokine receptor 5

UGT2A3

Gene (Entity type)

ENSG00000135220 - UDP glucuronosyltransferase family 2 member A3

MNS1

Gene (Entity type)

ENSG00000138587 - meiosis specific nuclear structural 1

NSL1

Gene (Entity type)

ENSG00000117697 - NSL1 component of MIS12 kinetochore complex

ATF1

Gene (Entity type)

ENSG00000123268 - activating transcription factor 1

CENPM

Gene (Entity type)

ENSG00000100162 - centromere protein M

MAN1A2

Gene (Entity type)

ENSG00000198162 - mannosidase alpha class 1A member 2

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.