PDE4D Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PDE4D Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PDE4D Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PDE4D Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PDE4D Up.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	MRPL40 Gene (Entity type)	ENSG00000185608 - mitochondrial ribosomal protein L40
	NOX1 Gene (Entity type)	ENSG00000007952 - NADPH oxidase 1
	MAPK14 Gene (Entity type)	ENSG00000112062 - mitogen-activated protein kinase 14
	COA3 Gene (Entity type)	ENSG00000183978 - cytochrome c oxidase assembly factor 3
	IFNAR1 Gene (Entity type)	ENSG00000142166 - interferon alpha and beta receptor subunit 1
	ATP6V1F Gene (Entity type)	ENSG00000128524 - ATPase H+ transporting V1 subunit F
	PRAF2 Gene (Entity type)	ENSG00000243279 - PRA1 domain family member 2
	SIRT5 Gene (Entity type)	ENSG00000124523 - sirtuin 5
	KAT7 Gene (Entity type)	ENSG00000136504 - lysine acetyltransferase 7

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

MRPL40

Gene (Entity type)

ENSG00000185608 - mitochondrial ribosomal protein L40

NOX1

Gene (Entity type)

ENSG00000007952 - NADPH oxidase 1

MAPK14

Gene (Entity type)

ENSG00000112062 - mitogen-activated protein kinase 14

COA3

Gene (Entity type)

ENSG00000183978 - cytochrome c oxidase assembly factor 3

IFNAR1

Gene (Entity type)

ENSG00000142166 - interferon alpha and beta receptor subunit 1

ATP6V1F

Gene (Entity type)

ENSG00000128524 - ATPase H+ transporting V1 subunit F

PRAF2

Gene (Entity type)

ENSG00000243279 - PRA1 domain family member 2

SIRT5

Gene (Entity type)

ENSG00000124523 - sirtuin 5

KAT7

Gene (Entity type)

ENSG00000136504 - lysine acetyltransferase 7

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.