GYPA Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GYPA Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GYPA Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GYPA Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GYPA Down.

Results found

Linked to

	Label	Description
	CHRM3 Gene (Entity type)	ENSG00000133019 - cholinergic receptor muscarinic 3
	GTPBP1 Gene (Entity type)	ENSG00000100226 - GTP binding protein 1
	ATP2C2 Gene (Entity type)	ENSG00000064270 - ATPase secretory pathway Ca2+ transporting 2
	FANCL Gene (Entity type)	ENSG00000115392 - FA complementation group L
	IRF2 Gene (Entity type)	ENSG00000168310 - interferon regulatory factor 2
	SAXO6 Gene (Entity type)	ENSG00000111554 - stabilizer of axonemal microtubules 6
	MTG1 Gene (Entity type)	ENSG00000148824 - mitochondrial ribosome associated GTPase 1
	PEX5 Gene (Entity type)	ENSG00000139197 - peroxisomal biogenesis factor 5
	SF3A2 Gene (Entity type)	ENSG00000104897 - splicing factor 3a subunit 2
	RUVBL2 Gene (Entity type)	ENSG00000183207 - RuvB like AAA ATPase 2

CHRM3

Gene (Entity type)

ENSG00000133019 - cholinergic receptor muscarinic 3

GTPBP1

Gene (Entity type)

ENSG00000100226 - GTP binding protein 1

ATP2C2

Gene (Entity type)

ENSG00000064270 - ATPase secretory pathway Ca2+ transporting 2

FANCL

Gene (Entity type)

ENSG00000115392 - FA complementation group L

IRF2

Gene (Entity type)

ENSG00000168310 - interferon regulatory factor 2

SAXO6

Gene (Entity type)

ENSG00000111554 - stabilizer of axonemal microtubules 6

MTG1

Gene (Entity type)

ENSG00000148824 - mitochondrial ribosome associated GTPase 1

PEX5

Gene (Entity type)

ENSG00000139197 - peroxisomal biogenesis factor 5

SF3A2

Gene (Entity type)

ENSG00000104897 - splicing factor 3a subunit 2

RUVBL2

Gene (Entity type)

ENSG00000183207 - RuvB like AAA ATPase 2

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.