PFKFB3 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PFKFB3 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PFKFB3 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PFKFB3 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PFKFB3 Down.

Results found

Linked to

	Label	Description
	HINT1 Gene (Entity type)	ENSG00000169567 - histidine triad nucleotide binding protein 1
	NDUFB6 Gene (Entity type)	ENSG00000165264 - NADH:ubiquinone oxidoreductase subunit B6
	TDP1 Gene (Entity type)	ENSG00000042088 - tyrosyl-DNA phosphodiesterase 1
	HOXB13 Gene (Entity type)	ENSG00000159184 - homeobox B13
	NOX1 Gene (Entity type)	ENSG00000007952 - NADPH oxidase 1
	PLA2G12A Gene (Entity type)	ENSG00000123739 - phospholipase A2 group XIIA
	ACYP2 Gene (Entity type)	ENSG00000170634 - acylphosphatase 2
	SPDEF Gene (Entity type)	ENSG00000124664 - SAM pointed domain containing ETS transcription factor
	HDHD5 Gene (Entity type)	ENSG00000069998 - haloacid dehalogenase like hydrolase domain containing 5
	GRHL2 Gene (Entity type)	ENSG00000083307 - grainyhead like transcription factor 2

HINT1

Gene (Entity type)

ENSG00000169567 - histidine triad nucleotide binding protein 1

NDUFB6

Gene (Entity type)

ENSG00000165264 - NADH:ubiquinone oxidoreductase subunit B6

TDP1

Gene (Entity type)

ENSG00000042088 - tyrosyl-DNA phosphodiesterase 1

HOXB13

Gene (Entity type)

ENSG00000159184 - homeobox B13

NOX1

Gene (Entity type)

ENSG00000007952 - NADPH oxidase 1

PLA2G12A

Gene (Entity type)

ENSG00000123739 - phospholipase A2 group XIIA

ACYP2

Gene (Entity type)

ENSG00000170634 - acylphosphatase 2

SPDEF

Gene (Entity type)

ENSG00000124664 - SAM pointed domain containing ETS transcription factor

HDHD5

Gene (Entity type)

ENSG00000069998 - haloacid dehalogenase like hydrolase domain containing 5

GRHL2

Gene (Entity type)

ENSG00000083307 - grainyhead like transcription factor 2

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.