MOCOS Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with MOCOS Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with MOCOS Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with MOCOS Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MOCOS Down.

Results found

Linked to

	Label	Description
	SDHD Gene (Entity type)	ENSG00000204370 - succinate dehydrogenase complex subunit D
	PPP2R5C Gene (Entity type)	ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma
	REL Gene (Entity type)	ENSG00000162924 - REL proto-oncogene, NF-kB subunit
	SPIB Gene (Entity type)	ENSG00000269404 - Spi-B transcription factor
	ARHGEF9 Gene (Entity type)	ENSG00000131089 - Cdc42 guanine nucleotide exchange factor 9
	MEP1A Gene (Entity type)	ENSG00000112818 - meprin A subunit alpha
	CHMP2B Gene (Entity type)	ENSG00000083937 - charged multivesicular body protein 2B
	ZNF430 Gene (Entity type)	ENSG00000118620 - zinc finger protein 430
	PPIP5K2 Gene (Entity type)	ENSG00000145725 - diphosphoinositol pentakisphosphate kinase 2
	PAQR3 Gene (Entity type)	ENSG00000163291 - progestin and adipoQ receptor family member 3

SDHD

Gene (Entity type)

ENSG00000204370 - succinate dehydrogenase complex subunit D

PPP2R5C

Gene (Entity type)

ENSG00000078304 - protein phosphatase 2 regulatory subunit B'gamma

REL

Gene (Entity type)

ENSG00000162924 - REL proto-oncogene, NF-kB subunit

SPIB

Gene (Entity type)

ENSG00000269404 - Spi-B transcription factor

ARHGEF9

Gene (Entity type)

ENSG00000131089 - Cdc42 guanine nucleotide exchange factor 9

MEP1A

Gene (Entity type)

ENSG00000112818 - meprin A subunit alpha

CHMP2B

Gene (Entity type)

ENSG00000083937 - charged multivesicular body protein 2B

ZNF430

Gene (Entity type)

ENSG00000118620 - zinc finger protein 430

PPIP5K2

Gene (Entity type)

ENSG00000145725 - diphosphoinositol pentakisphosphate kinase 2

PAQR3

Gene (Entity type)

ENSG00000163291 - progestin and adipoQ receptor family member 3

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.