PKM Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PKM Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PKM Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PKM Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PKM Down.

Results found

Linked to

	Label	Description
	POLD2 Gene (Entity type)	ENSG00000106628 - DNA polymerase delta 2, accessory subunit
	RPA1 Gene (Entity type)	ENSG00000132383 - replication protein A1
	CTR9 Gene (Entity type)	ENSG00000198730 - CTR9 component of Paf1/RNA polymerase II complex
	GRHPR Gene (Entity type)	ENSG00000137106 - glyoxylate and hydroxypyruvate reductase
	SRSF4 Gene (Entity type)	ENSG00000116350 - serine and arginine rich splicing factor 4
	ZFHX3 Gene (Entity type)	ENSG00000140836 - zinc finger homeobox 3
	TRRAP Gene (Entity type)	ENSG00000196367 - transformation/transcription domain associated protein
	KMT2A Gene (Entity type)	ENSG00000118058 - lysine methyltransferase 2A
	PRRC2A Gene (Entity type)	ENSG00000204469 - proline rich coiled-coil 2A
	NLGN1 Gene (Entity type)	ENSG00000169760 - neuroligin 1

POLD2

Gene (Entity type)

ENSG00000106628 - DNA polymerase delta 2, accessory subunit

RPA1

Gene (Entity type)

ENSG00000132383 - replication protein A1

CTR9

Gene (Entity type)

ENSG00000198730 - CTR9 component of Paf1/RNA polymerase II complex

GRHPR

Gene (Entity type)

ENSG00000137106 - glyoxylate and hydroxypyruvate reductase

SRSF4

Gene (Entity type)

ENSG00000116350 - serine and arginine rich splicing factor 4

ZFHX3

Gene (Entity type)

ENSG00000140836 - zinc finger homeobox 3

TRRAP

Gene (Entity type)

ENSG00000196367 - transformation/transcription domain associated protein

KMT2A

Gene (Entity type)

ENSG00000118058 - lysine methyltransferase 2A

PRRC2A

Gene (Entity type)

ENSG00000204469 - proline rich coiled-coil 2A

NLGN1

Gene (Entity type)

ENSG00000169760 - neuroligin 1

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Community

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.