GSE224547 CFTR knockout saliva-secreting gland 1 v 0 human dn (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE224547_CFTR knockout_saliva-secreting gland_1_v_0_human_dn.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE224547_CFTR knockout_saliva-secreting gland_1_v_0_human_dn.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE224547_CFTR knockout_saliva-secreting gland_1_v_0_human_dn.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE224547_CFTR knockout_saliva-secreting gland_1_v_0_human_dn.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	HDAC5 Gene (Entity type)	ENSG00000108840 - histone deacetylase 5
	LPAR2 Gene (Entity type)	ENSG00000064547 - lysophosphatidic acid receptor 2
	ULK1 Gene (Entity type)	ENSG00000177169 - unc-51 like autophagy activating kinase 1
	MCCC1 Gene (Entity type)	ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1
	MANBA Gene (Entity type)	ENSG00000109323 - mannosidase beta
	CASD1 Gene (Entity type)	ENSG00000127995 - CAS1 domain sialic acid O acetyltransferase 1
	KDM6B Gene (Entity type)	ENSG00000132510 - lysine demethylase 6B
	TMEM41B Gene (Entity type)	ENSG00000166471 - transmembrane protein 41B
	PPM1B Gene (Entity type)	ENSG00000138032 - protein phosphatase, Mg2+/Mn2+ dependent 1B

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

HDAC5

Gene (Entity type)

ENSG00000108840 - histone deacetylase 5

LPAR2

Gene (Entity type)

ENSG00000064547 - lysophosphatidic acid receptor 2

ULK1

Gene (Entity type)

ENSG00000177169 - unc-51 like autophagy activating kinase 1

MCCC1

Gene (Entity type)

ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

MANBA

Gene (Entity type)

ENSG00000109323 - mannosidase beta

CASD1

Gene (Entity type)

ENSG00000127995 - CAS1 domain sialic acid O acetyltransferase 1

KDM6B

Gene (Entity type)

ENSG00000132510 - lysine demethylase 6B

TMEM41B

Gene (Entity type)

ENSG00000166471 - transmembrane protein 41B

PPM1B

Gene (Entity type)

ENSG00000138032 - protein phosphatase, Mg2+/Mn2+ dependent 1B

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.