PDXK Up (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PDXK Up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PDXK Up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PDXK Up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PDXK Up.

Results found

Linked to

	Label	Description
	SIGIRR Gene (Entity type)	ENSG00000185187 - single Ig and TIR domain containing
	SH2B2 Gene (Entity type)	ENSG00000160999 - SH2B adaptor protein 2
	TMEM160 Gene (Entity type)	ENSG00000130748 - transmembrane protein 160
	THOC7 Gene (Entity type)	ENSG00000163634 - THO complex subunit 7
	CD3E Gene (Entity type)	ENSG00000198851 - CD3 epsilon subunit of T-cell receptor complex
	SULT1B1 Gene (Entity type)	ENSG00000173597 - sulfotransferase family 1B member 1
	PAK4 Gene (Entity type)	ENSG00000130669 - p21 (RAC1) activated kinase 4
	BATF3 Gene (Entity type)	ENSG00000123685 - basic leucine zipper ATF-like transcription factor 3
	TBXAS1 Gene (Entity type)	ENSG00000059377 - thromboxane A synthase 1
	PAFAH1B3 Gene (Entity type)	ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3

SIGIRR

Gene (Entity type)

ENSG00000185187 - single Ig and TIR domain containing

SH2B2

Gene (Entity type)

ENSG00000160999 - SH2B adaptor protein 2

TMEM160

Gene (Entity type)

ENSG00000130748 - transmembrane protein 160

THOC7

Gene (Entity type)

ENSG00000163634 - THO complex subunit 7

CD3E

Gene (Entity type)

ENSG00000198851 - CD3 epsilon subunit of T-cell receptor complex

SULT1B1

Gene (Entity type)

ENSG00000173597 - sulfotransferase family 1B member 1

PAK4

Gene (Entity type)

ENSG00000130669 - p21 (RAC1) activated kinase 4

BATF3

Gene (Entity type)

ENSG00000123685 - basic leucine zipper ATF-like transcription factor 3

TBXAS1

Gene (Entity type)

ENSG00000059377 - thromboxane A synthase 1

PAFAH1B3

Gene (Entity type)

ENSG00000079462 - platelet activating factor acetylhydrolase 1b catalytic subunit 3

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.