TIGAR Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with TIGAR Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with TIGAR Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with TIGAR Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TIGAR Down.

Results found

Linked to

	Label	Description
	PIK3CB Gene (Entity type)	ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
	ROCK2 Gene (Entity type)	ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2
	UVRAG Gene (Entity type)	ENSG00000198382 - UV radiation resistance associated
	PPM1D Gene (Entity type)	ENSG00000170836 - protein phosphatase, Mg2+/Mn2+ dependent 1D
	WWOX Gene (Entity type)	ENSG00000186153 - WW domain containing oxidoreductase
	JAK2 Gene (Entity type)	ENSG00000096968 - Janus kinase 2
	MNS1 Gene (Entity type)	ENSG00000138587 - meiosis specific nuclear structural 1
	ADAMTS3 Gene (Entity type)	ENSG00000156140 - ADAM metallopeptidase with thrombospondin type 1 motif 3
	ADAM22 Gene (Entity type)	ENSG00000008277 - ADAM metallopeptidase domain 22
	TPK1 Gene (Entity type)	ENSG00000196511 - thiamin pyrophosphokinase 1

PIK3CB

Gene (Entity type)

ENSG00000051382 - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

ROCK2

Gene (Entity type)

ENSG00000134318 - Rho associated coiled-coil containing protein kinase 2

UVRAG

Gene (Entity type)

ENSG00000198382 - UV radiation resistance associated

PPM1D

Gene (Entity type)

ENSG00000170836 - protein phosphatase, Mg2+/Mn2+ dependent 1D

WWOX

Gene (Entity type)

ENSG00000186153 - WW domain containing oxidoreductase

JAK2

Gene (Entity type)

ENSG00000096968 - Janus kinase 2

MNS1

Gene (Entity type)

ENSG00000138587 - meiosis specific nuclear structural 1

ADAMTS3

Gene (Entity type)

ENSG00000156140 - ADAM metallopeptidase with thrombospondin type 1 motif 3

ADAM22

Gene (Entity type)

ENSG00000008277 - ADAM metallopeptidase domain 22

TPK1

Gene (Entity type)

ENSG00000196511 - thiamin pyrophosphokinase 1

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Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.