GSE214505 AKR1B1 knockdown A-549 0 v 1 human up (Gene Set)

Dcc Asset:

rummageo gene perturbations.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE214505_AKR1B1 knockdown_A-549_0_v_1_human_up.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE214505_AKR1B1 knockdown_A-549_0_v_1_human_up.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE214505_AKR1B1 knockdown_A-549_0_v_1_human_up.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE214505_AKR1B1 knockdown_A-549_0_v_1_human_up.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	BRAF Gene (Entity type)	ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase
	CHMP2A Gene (Entity type)	ENSG00000130724 - charged multivesicular body protein 2A
	ARGLU1 Gene (Entity type)	ENSG00000134884 - arginine and glutamate rich 1
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	ERN1 Gene (Entity type)	ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1
	NRG1 Gene (Entity type)	ENSG00000157168 - neuregulin 1
	DYNLL2 Gene (Entity type)	ENSG00000264364 - dynein light chain LC8-type 2
	RAB7A Gene (Entity type)	ENSG00000075785 - RAB7A, member RAS oncogene family
	MCCC1 Gene (Entity type)	ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

BRAF

Gene (Entity type)

ENSG00000157764 - B-Raf proto-oncogene, serine/threonine kinase

CHMP2A

Gene (Entity type)

ENSG00000130724 - charged multivesicular body protein 2A

ARGLU1

Gene (Entity type)

ENSG00000134884 - arginine and glutamate rich 1

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

ERN1

Gene (Entity type)

ENSG00000178607 - endoplasmic reticulum to nucleus signaling 1

NRG1

Gene (Entity type)

ENSG00000157168 - neuregulin 1

DYNLL2

Gene (Entity type)

ENSG00000264364 - dynein light chain LC8-type 2

RAB7A

Gene (Entity type)

ENSG00000075785 - RAB7A, member RAS oncogene family

MCCC1

Gene (Entity type)

ENSG00000078070 - methylcrotonyl-CoA carboxylase subunit 1

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

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Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.