GSE118548 1 V 2 TRAMETINIB HUMAN UP (Gene Set)

Dcc Asset:

RummaGEO DrugPerturbations 2025.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

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Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with GSE118548 1 V 2 TRAMETINIB HUMAN UP.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with GSE118548 1 V 2 TRAMETINIB HUMAN UP.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with GSE118548 1 V 2 TRAMETINIB HUMAN UP.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GSE118548 1 V 2 TRAMETINIB HUMAN UP.

Results found

Linked to

	Label	Description
	PTPN12 Gene (Entity type)	ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12
	KDM5A Gene (Entity type)	ENSG00000073614 - lysine demethylase 5A
	HDAC6 Gene (Entity type)	ENSG00000094631 - histone deacetylase 6
	BLVRA Gene (Entity type)	ENSG00000106605 - biliverdin reductase A
	CPNE3 Gene (Entity type)	ENSG00000085719 - copine 3
	GSK3B Gene (Entity type)	ENSG00000082701 - glycogen synthase kinase 3 beta
	AGL Gene (Entity type)	ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase
	EXT2 Gene (Entity type)	ENSG00000151348 - exostosin glycosyltransferase 2
	PPIA Gene (Entity type)	ENSG00000196262 - peptidylprolyl isomerase A
	GRB2 Gene (Entity type)	ENSG00000177885 - growth factor receptor bound protein 2

PTPN12

Gene (Entity type)

ENSG00000127947 - protein tyrosine phosphatase non-receptor type 12

KDM5A

Gene (Entity type)

ENSG00000073614 - lysine demethylase 5A

HDAC6

Gene (Entity type)

ENSG00000094631 - histone deacetylase 6

BLVRA

Gene (Entity type)

ENSG00000106605 - biliverdin reductase A

CPNE3

Gene (Entity type)

ENSG00000085719 - copine 3

GSK3B

Gene (Entity type)

ENSG00000082701 - glycogen synthase kinase 3 beta

AGL

Gene (Entity type)

ENSG00000162688 - amylo-alpha-1,6-glucosidase and 4-alpha-glucanotransferase

EXT2

Gene (Entity type)

ENSG00000151348 - exostosin glycosyltransferase 2

PPIA

Gene (Entity type)

ENSG00000196262 - peptidylprolyl isomerase A

GRB2

Gene (Entity type)

ENSG00000177885 - growth factor receptor bound protein 2

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.