PLEKHM2 Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PLEKHM2 Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PLEKHM2 Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PLEKHM2 Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLEKHM2 Down.

Results found

Linked to

	Label	Description
	PAK3 Gene (Entity type)	ENSG00000077264 - p21 (RAC1) activated kinase 3
	GUCA2A Gene (Entity type)	ENSG00000197273 - guanylate cyclase activator 2A
	CALCB Gene (Entity type)	ENSG00000175868 - calcitonin related polypeptide beta
	NLK Gene (Entity type)	ENSG00000087095 - nemo like kinase
	LPCAT4 Gene (Entity type)	ENSG00000176454 - lysophosphatidylcholine acyltransferase 4
	SHANK2 Gene (Entity type)	ENSG00000162105 - SH3 and multiple ankyrin repeat domains 2
	MUC13 Gene (Entity type)	ENSG00000173702 - mucin 13, cell surface associated
	ARHGAP44 Gene (Entity type)	ENSG00000006740 - Rho GTPase activating protein 44
	TOB2 Gene (Entity type)	ENSG00000183864 - transducer of ERBB2, 2
	AQP8 Gene (Entity type)	ENSG00000103375 - aquaporin 8

PAK3

Gene (Entity type)

ENSG00000077264 - p21 (RAC1) activated kinase 3

GUCA2A

Gene (Entity type)

ENSG00000197273 - guanylate cyclase activator 2A

CALCB

Gene (Entity type)

ENSG00000175868 - calcitonin related polypeptide beta

NLK

Gene (Entity type)

ENSG00000087095 - nemo like kinase

LPCAT4

Gene (Entity type)

ENSG00000176454 - lysophosphatidylcholine acyltransferase 4

SHANK2

Gene (Entity type)

ENSG00000162105 - SH3 and multiple ankyrin repeat domains 2

MUC13

Gene (Entity type)

ENSG00000173702 - mucin 13, cell surface associated

ARHGAP44

Gene (Entity type)

ENSG00000006740 - Rho GTPase activating protein 44

TOB2

Gene (Entity type)

ENSG00000183864 - transducer of ERBB2, 2

AQP8

Gene (Entity type)

ENSG00000103375 - aquaporin 8

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.