PAM Down (Gene Set)

Dcc Asset:

LINCS L1000 CRISPR KO Consensus Sigs.gmt

Processed File (Entity type)

Dcc:

LINCS

DCC (Entity type)

Analyze

Playbook Workflow Builder: Gene Set Enrichment

Perform Gene Set Enrichment with this gene set against Common Fund program's gene sets, identifying significant overlaps using a pre-built PWB workflow. Run the workflow with PAM Down.

GeneSetCart

GeneSetCart helps you to fetch gene sets from various data sources, augment, combine with set operations, visualize and analyze these gene sets in a single session. Start a new session with PAM Down.

CFDE Gene Set Enrichment (GSE)

CFDE-GSE illuminates connections between the input gene set and various CF gene sets that overlap with the queried gene set. Query CFDE-GSE with PAM Down.

Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PAM Down.

Results found

Linked to

	Label	Description
	SPSB1 Gene (Entity type)	ENSG00000171621 - splA/ryanodine receptor domain and SOCS box containing 1
	EIF2AK2 Gene (Entity type)	ENSG00000055332 - eukaryotic translation initiation factor 2 alpha kinase 2
	GCC2 Gene (Entity type)	ENSG00000135968 - GRIP and coiled-coil domain containing 2
	ATP2A1 Gene (Entity type)	ENSG00000196296 - ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
	FEM1C Gene (Entity type)	ENSG00000145780 - fem-1 homolog C
	SSB Gene (Entity type)	ENSG00000138385 - small RNA binding exonuclease protection factor La
	MYOZ2 Gene (Entity type)	ENSG00000172399 - myozenin 2
	RAB6A Gene (Entity type)	ENSG00000175582 - RAB6A, member RAS oncogene family
	UBE2B Gene (Entity type)	ENSG00000119048 - ubiquitin conjugating enzyme E2 B
	MYBPC2 Gene (Entity type)	ENSG00000086967 - myosin binding protein C2

SPSB1

Gene (Entity type)

ENSG00000171621 - splA/ryanodine receptor domain and SOCS box containing 1

EIF2AK2

Gene (Entity type)

ENSG00000055332 - eukaryotic translation initiation factor 2 alpha kinase 2

GCC2

Gene (Entity type)

ENSG00000135968 - GRIP and coiled-coil domain containing 2

ATP2A1

Gene (Entity type)

ENSG00000196296 - ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1

FEM1C

Gene (Entity type)

ENSG00000145780 - fem-1 homolog C

SSB

Gene (Entity type)

ENSG00000138385 - small RNA binding exonuclease protection factor La

MYOZ2

Gene (Entity type)

ENSG00000172399 - myozenin 2

RAB6A

Gene (Entity type)

ENSG00000175582 - RAB6A, member RAS oncogene family

UBE2B

Gene (Entity type)

ENSG00000119048 - ubiquitin conjugating enzyme E2 B

MYBPC2

Gene (Entity type)

ENSG00000086967 - myosin binding protein C2

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CFDE Workbench

Consortium

Community

Resources

@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.