DUXB (Gene)

Omim:OMIM:618698

Id:42dee2c7-2a3b-58e7-8002-05aa4a6bc1f3

Hgnc:HGNC:33345

Description:double homeobox B

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View DUXB's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with DUXB.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using DUXB.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for DUXB.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with DUXB.

Results found

Linked to

	Label	Description
	GSE111247 temozolomide LN-308 0 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE192771 2 V 3 SORAFENIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 10 V 4 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE140322 imatinib K-562 C.M.L. 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE140322 SRSF1 overexpression K-562 C.M.L. Imatinib 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 0 V 12 LENALIDOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE182710 Drp1 TFAM overexpression 1 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE157109 TRIM8 knockdown MCF-7 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE111247 0 V 6 TEMOZOLOMIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE140322 3 V 1 IMATINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE111247 temozolomide LN-308 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE192771 2 V 3 SORAFENIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 10 V 4 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE140322 imatinib K-562 C.M.L. 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE140322 SRSF1 overexpression K-562 C.M.L. Imatinib 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 0 V 12 LENALIDOMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE182710 Drp1 TFAM overexpression 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE157109 TRIM8 knockdown MCF-7 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE111247 0 V 6 TEMOZOLOMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE140322 3 V 1 IMATINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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