ERVV-2 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:100271846, ENVV2, ERVV-2, HERV-V2, HGNC:39051, NM_001191055, NP_001177984, endogenous retrovirus group V member 2, envelope

Id:ENSG00000268964

Hgnc:HGNC:39051

Entrez:100271846

Ensembl:ENSG00000268964

Description:endogenous retrovirus group V member 2, envelope

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on human chromosome 19 that has inactivating mutations in the gag and pol genes. This envelope glycoprotein gene appears to have been selectively preserved. The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic activity in humans and other primate lineages. [provided by RefSeq, Jun 2015]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View ERVV-2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with ERVV-2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using ERVV-2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for ERVV-2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with ERVV-2.

Results found

Linked to

	Label	Description
	GSE192860 0 V 1 TRIFLUOPERAZINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 digoxin 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE203329 HCC knockout 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE169152 5 V 7 IBRUTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE120792 BRCA1 inhibition Interferons 1 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193258,GSE193259 5 V 1 OSIMERTINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE128730 neratinib OVCAR-8 4 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE115542 2 V 0 DIGOXIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE154936 3 V 4 REMDESIVIR HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE128730 4 V 5 NERATINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE192860 0 V 1 TRIFLUOPERAZINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 digoxin 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE203329 HCC knockout 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE169152 5 V 7 IBRUTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE120792 BRCA1 inhibition Interferons 1 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193258,GSE193259 5 V 1 OSIMERTINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE128730 neratinib OVCAR-8 4 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE115542 2 V 0 DIGOXIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE154936 3 V 4 REMDESIVIR HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE128730 4 V 5 NERATINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.