PLA2G4B (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:100137049, HGNC:9036, HsT16992, MIM:606088, NM_001114633, NP_001108105, PLA2G4B, cPLA2-beta, phospholipase A2 group IVB

Omim:OMIM:606088

Id:5c77d29f-ac8d-5e2a-a962-34356177b4fc

Hgnc:HGNC:9036

Entrez:100137049

Ensembl:ENSG00000243708

Description:phospholipase A2 group IVB

This gene encodes a member of the cytosolic phospholipase A2 protein family. Phospholipase A2 enzymes hydrolyze the sn-2 bond of phospholipids, releasing lysophospholipids and fatty acids. This enzyme may be associated with mitochondria and early endosomes. Most tissues also express read-through transcripts from the upstream gene into this gene, some of which may encode fusion proteins combining the N-terminus of the upstream gene including its JmjC domain with the almost complete coding region of this gene, including the C2 and cytoplasmic phospholipase A2 domains. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View PLA2G4B's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with PLA2G4B.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using PLA2G4B.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for PLA2G4B.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with PLA2G4B.

Results found

Linked to

	Label	Description
	GSE173116 GSE173118 ML-7 8 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	T62-Spleen Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE233679 5 V 15 NICOTINAMIDE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE233679 nicotinamide 14 v 15 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE60217 adenosine 1 v 9 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 5 v 3 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE60691 2 V 1 GLUTAMINE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE242290 1 V 11 GLUTATHIONE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE60217 1 V 9 INOSINE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE173116 GSE173118 ML-7 8 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

T62-Spleen Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE233679 5 V 15 NICOTINAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 7 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE233679 nicotinamide 14 v 15 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE60217 adenosine 1 v 9 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE97616 GSE97617 NOK overexpression HEK RNA Small Interfering 5 v 3 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE60691 2 V 1 GLUTAMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE242290 1 V 11 GLUTATHIONE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE60217 1 V 9 INOSINE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.