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GABRG3 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ENTREZ:2567, GABRG3, HGNC:4088, MIM:600233, NM_001270873, NM_033223, NP_001257802, NP_150092, XM_011521430, XM_011521431, XM_017022058, XM_017022059, XM_017022060, XM_024449889, XP_011519732, XP_011519733, XP_016877547, XP_016877548, XP_016877549, XP_024305657, gamma-aminobutyric acid type A receptor subunit gamma3
Omim:OMIM:600233
Id:087b85c0-672c-55d7-965b-f8bc08e9d706
Hgnc:HGNC:4088
Entrez:2567
Ensembl:ENSG00000182256
Description:gamma-aminobutyric acid type A receptor subunit gamma3
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. The protein encoded by this gene is a gamma subunit, which contains the benzodiazepine binding site. Two transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2012]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View GABRG3's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with GABRG3.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using GABRG3.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for GABRG3.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with GABRG3.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE187006 3 V 2 VALPROIC ACID HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 7 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE100148 EZH2 inhibition 10 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876 GSE147877 enzalutamide MR42D 4 v 10 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE218378 PBX1 overexpression HCT 116 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876,GSE147877 4 V 10 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213588 9 V 3 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE149632 dopamine 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 7 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE161073 IDH1 inhibition 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE187006 3 V 2 VALPROIC ACID HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 7 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE100148 EZH2 inhibition 10 v 5 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876 GSE147877 enzalutamide MR42D 4 v 10 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE218378 PBX1 overexpression HCT 116 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876,GSE147877 4 V 10 ENZALUTAMIDE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213588 9 V 3 TRAMETINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE149632 dopamine 0 v 6 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE265788 IDH1 inhibition RNA-Directed DNA Polymerase 7 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE161073 IDH1 inhibition 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.