CASC2 (Gene)

Entrez:255082

Description:cancer susceptibility 2

Involved in defense response to tumor cell; negative regulation of MAPK cascade; and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. [provided by Alliance of Genome Resources, Apr 2022]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CASC2's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CASC2.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CASC2.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CASC2.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CASC2.

Results found

Linked to

	Label	Description
	GSE119978 GSE180930 cisplatin 6 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE189035 inositol 2 v 4 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE155162 GSE155169 buparlisib 1 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE172016 paclitaxel 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE115395 enzalutamide LNCaP 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE224004 GSE224005 CHD4 EWS-FLI1 knockdown 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE218060 decitabine T cell 7 v 0 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE126651 PRMT5 MTAP inhibition 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE236896 GSE237665 DNMT EZH2 inhibition 6 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE156761 dopamine neuron 0 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS

GSE119978 GSE180930 cisplatin 6 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE189035 inositol 2 v 4 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE155162 GSE155169 buparlisib 1 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE172016 paclitaxel 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE115395 enzalutamide LNCaP 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE224004 GSE224005 CHD4 EWS-FLI1 knockdown 0 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE218060 decitabine T cell 7 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE126651 PRMT5 MTAP inhibition 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE236896 GSE237665 DNMT EZH2 inhibition 6 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE156761 dopamine neuron 0 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.