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APEH (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:AARE, ACPH, APEH, APH, D3F15S2, D3S48E, DNF15S2, ENTREZ:327, HGNC:586, MIM:102645, NM_001640, NP_001631, OPH, XM_005265097, XM_005265098, XM_011533658, XM_011533661, XM_011533662, XM_011533663, XM_017006285, XM_017006286, XM_024453499, XM_024453500, XM_024453501, XM_024453502, XM_024453503, XM_024453504, XM_024453505, XM_024453506, XM_024453507, XP_005265154, XP_005265155, XP_011531960, XP_011531963, XP_011531964, XP_011531965, XP_016861774, XP_016861775, XP_024309267, XP_024309268, XP_024309269, XP_024309270, XP_024309271, XP_024309272, XP_024309273, XP_024309274, XP_024309275, acylaminoacyl-peptide hydrolase
Omim:OMIM:102645
Id:ENSG00000164062
Hgnc:HGNC:586
Entrez:327
Ensembl:ENSG00000164062
Description:acylaminoacyl-peptide hydrolase
This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma. [provided by RefSeq, Jul 2008]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View APEH's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with APEH.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using APEH.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for APEH.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with APEH.

Results found

Linked to

 

Label

Description

 

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GSE102757 1 V 0 PANOBINOSTAT MOUSE UP

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Gene Set (Entity type)

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GSE195663 cisplatin 0 v 1 human up

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A Gene Set from LINCS

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GSE77108 saha 0 v 9 human up

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GSE228430 FABP5 inhibition Huh-7 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

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GSE120210 GSE120214 TBXT brachyury inhibition 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE252944 AKT inhibition 10 v 15 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE172016 2 V 5 PACLITAXEL HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE168473 0 V 1 ISONIAZID HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE102757 1 V 0 PANOBINOSTAT MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE207871 NPC knockdown S18 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE128730 3 V 5 NERATINIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE195663 cisplatin 0 v 1 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE77108 saha 0 v 9 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE228430 FABP5 inhibition Huh-7 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE120210 GSE120214 TBXT brachyury inhibition 4 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

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    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
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