Synonyms:ARNIP, CHIMP, ENTREZ:25898, HGNC:17479, MIM:607680, NM_001008925, NM_001009922, NM_001278536, NM_001278537, NM_001278538, NM_001278539, NM_001387136, NM_001387137, NM_015436, NP_001009922, NP_001265465, NP_001265466, NP_001265467, NP_001265468, NP_001374065, NP_001374066, NP_056251, NR_037913, NR_037914, NR_103723, NR_103724, NR_103725, PIRH2, PRO1996, RCHY1, RNF199, XM_024453984, XP_024309752, ZCHY, ZNF363, ring finger and CHY zinc finger domain containing 1
Id:ENSG00000163743
Description:ring finger and CHY zinc finger domain containing 1
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013]