CYP11B1 (Gene)

Organism:

Homo sapiens

Synonyms:CPN1, CYP11B, CYP11B1, ENTREZ:1584, FHI, HGNC:2591, MIM:610613, NM_000497, NM_001026213, NP_000488, NP_001021384, P450C11, cytochrome P450 family 11 subfamily B member 1

Omim:OMIM:610613

Id:ENSG00000160882

Hgnc:HGNC:2591

Entrez:1584

Ensembl:ENSG00000160882

Description:cytochrome P450 family 11 subfamily B member 1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CYP11B1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CYP11B1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CYP11B1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CYP11B1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CYP11B1.

Results found

Linked to

	Label	Description
	GSE264621 1 V 6 SECRETIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE264621 1 V 3 SECRETIN HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE200099 honokiol U-937 THP-1 3 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE200099 3 V 1 HONOKIOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE146687 irinotecan 2 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	MATK Up Gene Set (Entity type)	A Gene Set from LINCS
	BIBN-4096 Up Gene Set (Entity type)	A Gene Set from LINCS
	SLC6A11 Down Gene Set (Entity type)	A Gene Set from LINCS
	Amorolfine Down Gene Set (Entity type)	A Gene Set from LINCS
	TAS2R60 Up Gene Set (Entity type)	A Gene Set from LINCS

GSE264621 1 V 6 SECRETIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE264621 1 V 3 SECRETIN HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE200099 honokiol U-937 THP-1 3 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE200099 3 V 1 HONOKIOL HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE146687 irinotecan 2 v 1 human up

Gene Set (Entity type)

A Gene Set from LINCS

MATK Up

Gene Set (Entity type)

A Gene Set from LINCS

BIBN-4096 Up

Gene Set (Entity type)

A Gene Set from LINCS

SLC6A11 Down

Gene Set (Entity type)

A Gene Set from LINCS

Amorolfine Down

Gene Set (Entity type)

A Gene Set from LINCS

TAS2R60 Up

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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