NCOR1 (Gene)

Organism:

Homo sapiens

Synonyms:ENTREZ:9611, HGNC:7672, MIM:600849, N-CoR, N-CoR1, NCOR1, NM_001190438, NM_001190440, NM_006311, NP_001177367, NP_001177369, NP_006302, PPP1R109, TRAC1, XM_005256866, XM_005256868, XM_005256871, XM_005256872, XM_005256873, XM_005256874, XM_005256875, XM_006721601, XM_006721602, XM_006721603, XM_006721604, XM_011524083, XM_011524084, XM_011524085, XM_011524086, XM_017025396, XM_017025397, XM_017025398, XM_017025399, XM_017025400, XM_017025401, XM_017025402, XM_017025403, XM_017025404, XM_017025405, XM_017025406, XM_017025407, XM_017025408, XM_017025409, XM_017025410, XM_017025411, XM_017025412, XM_017025413, XM_017025414, XM_017025415, XM_017025416, XM_017025417, XM_017025418, XM_017025419, XM_017025420, XM_024451041, XM_024451042, XM_024451043, XP_005256923, XP_005256925, XP_005256928, XP_005256929, XP_005256930, XP_005256931, XP_005256932, XP_006721664, XP_006721665, XP_006721666, XP_006721667, XP_011522385, XP_011522386, XP_011522387, XP_011522388, XP_016880885, XP_016880886, XP_016880887, XP_016880888, XP_016880889, XP_016880890, XP_016880891, XP_016880892, XP_016880893, XP_016880894, XP_016880895, XP_016880896, XP_016880897, XP_016880898, XP_016880899, XP_016880900, XP_016880901, XP_016880902, XP_016880903, XP_016880904, XP_016880905, XP_016880906, XP_016880907, XP_016880908, XP_016880909, XP_024306809, XP_024306810, XP_024306811, hN-CoR, nuclear receptor corepressor 1

Omim:OMIM:600849

Id:ENSG00000141027

Hgnc:HGNC:7672

Entrez:9611

Ensembl:ENSG00000141027

Description:nuclear receptor corepressor 1

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View NCOR1's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with NCOR1.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using NCOR1.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for NCOR1.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with NCOR1.

Results found

Linked to

	Label	Description
	GSE186471 1 V 2 CARNOSOL HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE158834 ADIPOR2 knockout HEK293 1 v 6 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE202434 GSE202438 talazoparib 6 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE197555 0 V 3 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE77108 8 V 7 SAHA HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE216043 cisplatin 11 v 2 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE169356 ivermectin prostate gland 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE139987 1 V 0 ROSIGLITAZONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE169356 FOXA1 inhibition prostate gland Ivermectin 0 v 1 human up Gene Set (Entity type)	A Gene Set from LINCS