Synonyms:ENTREZ:6821, HGNC:11460, MIM:606887, NM_000456, NM_001032386, NM_001032387, NP_000447, NP_001027558, NP_001027559, SUOX, XM_017019905, XM_017019906, XM_017019907, XM_017019908, XM_024449167, XP_016875394, XP_016875395, XP_016875396, XP_016875397, XP_024304935, sulfite oxidase
Omim:OMIM:606887
Id:13f3c167-473c-5c8d-be0c-28944b4be7c4
Hgnc:HGNC:11460
Description:sulfite oxidase
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]