SDS (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Synonyms:ENTREZ:10993, HGNC:10691, MIM:182128, NM_006843, NP_006834, SDH, SDS, serine dehydratase

Omim:OMIM:182128

Id:ENSG00000135094

Hgnc:HGNC:10691

Entrez:10993

Ensembl:ENSG00000135094

Description:serine dehydratase

This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View SDS's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with SDS.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using SDS.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for SDS.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with SDS.

Results found

Linked to

	Label	Description
	GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE144843 GSE144844 SMARCA2 SMARCA4 knockdown 0 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE150244 TRIM8 knockout 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE62843,GSE64371 2 V 5 FURAN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE218580 1 V 4 FENTANYL MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE199107 tryptophan 6 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE218879 1 V 0 ACETAMINOPHEN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE169155 3 V 0 ACETAMINOPHEN MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE159678 hydroxychloroquine 4 v 7 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE212231 GSE218491 SHP2 inhibition 3 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE144843 GSE144844 SMARCA2 SMARCA4 knockdown 0 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE157050,GSE157051 2 V 3 METFORMIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE150244 TRIM8 knockout 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE62843,GSE64371 2 V 5 FURAN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE218580 1 V 4 FENTANYL MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE199107 tryptophan 6 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE218879 1 V 0 ACETAMINOPHEN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE169155 3 V 0 ACETAMINOPHEN MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE159678 hydroxychloroquine 4 v 7 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.