Synonyms:ENTREZ:79088, HGNC:20725, K-RBP, NM_001300883, NM_001318055, NM_001318056, NM_024106, NP_001287812, NP_001304984, NP_001304985, NP_077011, XM_017027293, XM_017027294, XM_024451702, XM_024451703, XM_024451704, XM_024451705, XP_016882782, XP_016882783, XP_024307470, XP_024307471, XP_024307472, XP_024307473, ZNF426, zinc finger protein 426
Id:ENSG00000130818
Hgnc:HGNC:20725
Description:zinc finger protein 426
Kaposi's sarcoma-associated herpesvirus (KSHV) can be reactivated from latency by the viral protein RTA. The protein encoded by this gene is a zinc finger transcriptional repressor that interacts with RTA to modulate RTA-mediated reactivation of KSHV. While the encoded protein can repress KSHV reactivation, RTA can induce degradation of this protein through the ubiquitin-proteasome pathway to overcome the repression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]