TNNI3K (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Synonyms:CARK, CCDD, ENTREZ:51086, HGNC:19661, MIM:613932, NM_015978, NP_057062, TNNI3 interacting kinase, TNNI3K

Omim:OMIM:613932

Id:ENSG00000116783

Hgnc:HGNC:19661

Entrez:51086

Ensembl:ENSG00000116783

Description:TNNI3 interacting kinase

This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology. [provided by RefSeq, Sep 2012]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TNNI3K's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TNNI3K.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TNNI3K.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TNNI3K.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TNNI3K.

Results found

Linked to

	Label	Description
	GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE217115 2 V 0 ALECTINIB MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE218580 1 V 0 FENTANYL MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE146982 metformin 0 v 6 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE252857 1 V 0 PREDNISONE MOUSE DN Gene Set (Entity type)	A Gene Set from LINCS
	T66-Lung Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE126651 PRMT5 MTAP inhibition 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE115384 CELSR2 knockdown 6 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 4 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE226114,GSE226116 2 V 0 DOXORUBICIN MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE217115 2 V 0 ALECTINIB MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE218580 1 V 0 FENTANYL MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE146982 metformin 0 v 6 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE252857 1 V 0 PREDNISONE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

T66-Lung Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 2 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE126651 PRMT5 MTAP inhibition 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE115384 CELSR2 knockdown 6 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE195559 NOTCH1 knockout endothelial cell cardiac muscle cell stem cell 6 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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