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MED23 (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:ARC130, CRSP130, CRSP133, CRSP3, DRIP130, ENTREZ:9439, HGNC:2372, MED23, MIM:605042, MRT18, NM_001270521, NM_001270522, NM_001376517, NM_001376518, NM_001376519, NM_001376520, NM_001376521, NM_001376522, NM_001376523, NM_001376524, NM_004830, NM_015979, NP_001257450, NP_001257451, NP_001363446, NP_001363447, NP_001363448, NP_001363449, NP_001363450, NP_001363451, NP_001363452, NP_001363453, NP_004821, NP_057063, SUR-2, SUR2, XM_006715612, XM_011536257, XM_017011501, XP_006715675, XP_011534559, XP_016866990, mediator complex subunit 23
Omim:OMIM:605042
Id:ENSG00000112282
Hgnc:HGNC:2372
Entrez:9439
Ensembl:ENSG00000112282
Description:mediator complex subunit 23
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MED23's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MED23.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MED23.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MED23.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MED23.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE146687 2 V 5 ERIBULIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147876,GSE147877 2 V 7 ENZALUTAMIDE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE125782 3 V 1 GLUTAMINE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE158431 2 V 0 PIOGLITAZONE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE137325 2 V 0 COPANLISIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE171177,GSE171181 1 V 0 E7107 HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE189859 GSE189861 IDH1 knockout 4 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE158834 ADIPOR2 knockout HEK293 7 v 13 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE165548 2 V 13 GEMCITABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE119007 prostaglandin TS-A clone E2 1 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE146687 2 V 5 ERIBULIN HUMAN DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147876,GSE147877 2 V 7 ENZALUTAMIDE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE125782 3 V 1 GLUTAMINE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE158431 2 V 0 PIOGLITAZONE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE137325 2 V 0 COPANLISIB HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE171177,GSE171181 1 V 0 E7107 HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE189859 GSE189861 IDH1 knockout 4 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE158834 ADIPOR2 knockout HEK293 7 v 13 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE165548 2 V 13 GEMCITABINE HUMAN UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE119007 prostaglandin TS-A clone E2 1 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.