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HTR2A (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)
Synonyms:5-HT2A, 5-hydroxytryptamine receptor 2A, ENTREZ:3356, HGNC:5293, HTR2, HTR2A, MIM:182135, NM_000621, NM_001165947, NM_001378924, NP_000612, NP_001159419, NP_001365853
Id:ENSG00000102468
Entrez:3356
Ensembl:ENSG00000102468
Description:5-hydroxytryptamine receptor 2A
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Analyze

Data Distillery
CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View HTR2A's neighborhood in the knowledge graph.

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Playbook Workflow Builder
Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with HTR2A.

Gene Partnership Appyter
CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using HTR2A.

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Gene and Drug Landing Page Aggregator
GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for HTR2A.

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Playbook Workflow Builder
Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with HTR2A.

Results found

Linked to

 

Label

Description

 

Gene Set

GSE110178 2 V 3 TRANYLCYPROMINE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147662 3 V 1 NICOTINAMIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE108464 AZ-628 1 v 2 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE238116 EGR1 HCC overexpression MHCC97-H PLC-PRF-5 3 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213845 EZH2 inhibition 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE213845 EZH2 inhibition 4 v 0 human dn

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE147662 2 V 5 NICOTINAMIDE MOUSE DN

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE248858 4 V 7 TCPOBOP MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

Gene Set

GSE217441,GSE217443 1 V 0 IVOSIDENIB MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

  • Gene Set

    GSE110178 2 V 3 TRANYLCYPROMINE MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147662 3 V 1 NICOTINAMIDE MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE205976 GSE205978 CEP83 knockout TIME 1 v 4 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE108464 AZ-628 1 v 2 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE238116 EGR1 HCC overexpression MHCC97-H PLC-PRF-5 3 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213845 EZH2 inhibition 2 v 0 human up

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE213845 EZH2 inhibition 4 v 0 human dn

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE147662 2 V 5 NICOTINAMIDE MOUSE DN

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE248858 4 V 7 TCPOBOP MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

  • Gene Set

    GSE217441,GSE217443 1 V 0 IVOSIDENIB MOUSE UP

    Gene Set (Entity type)

    A Gene Set from LINCS

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    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    Consortium
    About the CFDECF ProgramsCFDE CentersPartnershipsPilot Projects
    Community
    Workbench TutorialTraining & OutreachDocumentationGet QR CodesFunding Opportunities
    Resources
    Data & MetadataToolsChatbotUse CasesPublications
    CFDE Workbench
    Report a bug
    The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.
    @CFDE Workbench 2026
    This repository is under review for potential modification in compliance with Administration directives.