CD40LG (Gene)

Organism:

Homo sapiens

Synonyms:CD154, CD40 ligand, CD40L, CD40LG, ENTREZ:959, HGNC:11935, HIGM1, IGM, IMD3, MIM:300386, NM_000074, NP_000065, T-BAM, TNFSF5, TRAP, gp39, hCD40L

Id:ENSG00000102245

Entrez:959

Ensembl:ENSG00000102245

Description:CD40 ligand

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View CD40LG's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with CD40LG.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using CD40LG.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for CD40LG.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with CD40LG.

Results found

Linked to

	Label	Description
	GSE114883 0 V 5 ROMIDEPSIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE76425 0 V 12 LENALIDOMIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 ruxolitinib 1 v 2 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE110248 1 V 6 ROMIDEPSIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 5 V 13 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE221577 PIK3R1 knockout 1 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE159678 hydroxychloroquine 6 v 7 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 4 V 0 RUXOLITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	T66-Lung Consensus Gene Set (Entity type)	A Gene Set from MoTrPAC
	GSE182680 GSE182683 dexamethasone 0 v 11 human dn Gene Set (Entity type)	A Gene Set from LINCS

GSE114883 0 V 5 ROMIDEPSIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE76425 0 V 12 LENALIDOMIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 ruxolitinib 1 v 2 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE110248 1 V 6 ROMIDEPSIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 5 V 13 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE221577 PIK3R1 knockout 1 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE159678 hydroxychloroquine 6 v 7 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 4 V 0 RUXOLITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

T66-Lung Consensus

Gene Set (Entity type)

A Gene Set from MoTrPAC

GSE182680 GSE182683 dexamethasone 0 v 11 human dn

Gene Set (Entity type)

A Gene Set from LINCS

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The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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