TXK (Gene)

Organism:

Homo sapiens

Synonyms:BTKL, ENTREZ:7294, HGNC:12434, MIM:600058, NM_003328, NP_003319, PSCTK5, PTK4, RLK, TKL, TXK tyrosine kinase, TXK, XM_011513747, XM_011513748, XM_017008581, XM_017008582, XM_024454200, XP_011512049, XP_011512050, XP_016864070, XP_016864071, XP_024309968, XR_925166

Omim:OMIM:600058

Nci:C162444

Id:ENSG00000074966

Hgnc:HGNC:12434

Entrez:7294

Ensembl:ENSG00000074966

Description:TXK tyrosine kinase

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Involved in positive regulation of interferon-gamma-mediated signaling pathway; positive regulation of macromolecule metabolic process; and protein autophosphorylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Analyze

CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View TXK's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with TXK.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using TXK.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for TXK.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with TXK.

Results found

Linked to

	Label	Description
	GSE195663 cisplatin 7 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE226285 3 V 0 GLUTATHIONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE148200 0 V 2 GEMCITABINE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE182680,GSE182683 7 V 3 DEXAMETHASONE HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE130401 4 V 3 TRAMETINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE238213 dopamine 2 v 0 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE114883 0 V 5 ROMIDEPSIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE149901 3 V 1 ANLOTINIB HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE172016 paclitaxel 2 v 5 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE195663 7 V 1 CISPLATIN HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS

GSE195663 cisplatin 7 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE226285 3 V 0 GLUTATHIONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE148200 0 V 2 GEMCITABINE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE182680,GSE182683 7 V 3 DEXAMETHASONE HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE130401 4 V 3 TRAMETINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE238213 dopamine 2 v 0 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE114883 0 V 5 ROMIDEPSIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE149901 3 V 1 ANLOTINIB HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE172016 paclitaxel 2 v 5 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE195663 7 V 1 CISPLATIN HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

This repository is under review for potential modification in compliance with Administration directives.