MYOC (Gene)

Organism:

Homo sapiens

Taxonomy (Entity type)

Synonyms:ENTREZ:4653, GLC1A, GPOA, HGNC:7610, JOAG, JOAG1, MIM:601652, MYOC, NM_000261, NP_000252, TIGR, myocilin

Omim:OMIM:601652

Id:ENSG00000034971

Hgnc:HGNC:7610

Entrez:4653

Ensembl:ENSG00000034971

Description:myocilin

MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]

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CFDE DD-Knowledge Graph

The CFDE Data Distillery Knowledge Graph contains entities and relationships across the CFDE. View MYOC's neighborhood in the knowledge graph.

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Playbook Workflow Builder: Gene-Centric Workflow

View Gene-Centric information about the gene from a pre-built PWB workflow. View the workflow with MYOC.

CFDE Gene-Centric Appyter

The CFDE Gene Centric Appyter Resolves and Displays Gene-Centric information from CFDE APIs. Execute the Appyter using MYOC.

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GDLPA Landing Pages Links

The Gene and Drug Landing Page Aggregator (GDLPA) finds links to primary and secondary source information from CFDE and other resources. Discover landing pages for MYOC.

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Playbook Workflow Builder

The Playbook Workflow Builder helps you interactively construct workflows leveraging CFDE APIs without code. Start a new workflow with MYOC.

Results found

Linked to

	Label	Description
	GSE213588 trametinib NF1 8 v 11 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE95077 1 V 2 AMILORIDE HUMAN DN Gene Set (Entity type)	A Gene Set from LINCS
	GSE128240 0 V 1 CYCLOPHOSPHAMIDE MOUSE UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 8 V 11 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE113369 p53 inhibition 2 v 3 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE193739 CGA knockdown 2 v 1 human dn Gene Set (Entity type)	A Gene Set from LINCS
	GSE193351 4 V 0 RUXOLITINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE113369 p53 inhibition 2 v 5 human up Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 9 V 5 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS
	GSE213588 8 V 5 TRAMETINIB HUMAN UP Gene Set (Entity type)	A Gene Set from LINCS

GSE213588 trametinib NF1 8 v 11 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE95077 1 V 2 AMILORIDE HUMAN DN

Gene Set (Entity type)

A Gene Set from LINCS

GSE128240 0 V 1 CYCLOPHOSPHAMIDE MOUSE UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 8 V 11 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE113369 p53 inhibition 2 v 3 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE193739 CGA knockdown 2 v 1 human dn

Gene Set (Entity type)

A Gene Set from LINCS

GSE193351 4 V 0 RUXOLITINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE113369 p53 inhibition 2 v 5 human up

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 9 V 5 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

GSE213588 8 V 5 TRAMETINIB HUMAN UP

Gene Set (Entity type)

A Gene Set from LINCS

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@CFDE Workbench 2026

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

Consortium

Community

Resources

CFDE Workbench

The CFDE Workbench is actively being developed and maintained by the CFDE Data Resource Center (DRC).The DRC is funded by OT2OD036435 from the Common Fund at the National Institutes of Health.

@CFDE Workbench 2026

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