Description:Galactooligosaccharides (GOS) and Lactobacillus reuteri are well-known prebiotic and probiotic, respectively, with great benefits in microbial balance and intestinal barrier function. L. reuteri can utilize GOS as a carbon resource, providing the foundation for synbiotic development.It is important to identify the intestinal bacteria and metabolites regulated by the synbiotic and then the beneficial effects of identified intestinal bacteria and metabolites will be evaluated in animals with gut inflammation via cytokines detection and metabolomics.