PR002727 (Project)

Dcc Asset:

MW submission packet 20260611.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Child Project:

PPR00001

Project (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M85C20

Description:To investigate the functional changes of gut microbiota, we collected feces (2-3 pellets) from Sle1.Yaa lupus-prone mice treated with Faecalibacterium prausnitzii strain UT1 versus PBS (every other day for 3 months). The untargeted fecal metabolomes of the two groups of mice were analyzed by LC-MS. Data demonstrated that UT1 treatment induced profound metabolic changes of the gut microbiota, leading to sustain activities of pentose phosphate pathway and tryptophan metabolism. These data were integrated with metagenomics and metatranscriptomics data of the same fecal samples to correlatively elucidate the functional programming of the microbiota by probiotic UT1 bacterium.

Results found

Linked to

	Label	Description
	SU004465 Subject (Entity type)	A subject produced as part of the PR002727 project
	ST004311 Rawdata.zip File (Entity type)	A 543 MB file from Metabolomics produced from OBI:0003097 as part of the PR002727 project
	SA505504 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505512 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505508 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505513 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505509 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505505 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505510 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project
	SA505511 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002727 project

SU004465

Subject (Entity type)

A subject produced as part of the PR002727 project

ST004311 Rawdata.zip

File (Entity type)

A 543 MB file from Metabolomics produced from OBI:0003097 as part of the PR002727 project

SA505504

Biosample (Entity type)