PR002248 (Project)

Dcc Asset:

MW submission packet 20260310.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Child Project:

PPR00001

Project (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8224Q

Description:In order to investigate metabolites both secreted from and enriched in cells upon ferroptotic cell death, we compared metabolomes from supernatants and lysates of ferroptotic to nonferroptotic Pfa1 cells after 24 h(cells are alive), 30 h (ferroptosis is present) as well as supernatants after 72 h (no cells left). In Pfa1 cells, ferroptosis is induced upon treatment with tamoxifen which induces knock-out of GPX4, causing massive ferroptosis. Ferroptosis, in turn, was rescued using lipid ros scavenger FER-1 (Ferrostatin1).

Results found

Linked to

	Label	Description
	SA393847 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SU003765 Subject (Entity type)	A subject produced as part of the PR002248 project
	SA393832 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393888 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393802 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393783 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393860 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393859 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393883 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project
	SA393900 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR002248 project