PR001129 (Project)

Dcc Asset:

MW submission packet 20260611.zip

Processed File (Entity type)

Dcc:

Metabolomics

DCC (Entity type)

Child Project:

PPR00001

Project (Entity type)

Persistent Id:http://dx.doi.org/10.21228/M8RX1D

Description:To uncover links between metabolism and disease severity in murine malaria, we performed plasma metabolomics via Metabolon on eight inbred, Plasmodium chabaudi-infected mouse strains with diverse disease phenotypes. We sacrificed and collected plasma from >=3 mice per strain per day of acute infection alongside uninfected control mice (approximately days 5-12 depending on mouse strain). We collected disease severity data, e.g. weight loss, liver enzymes, and anemia, concurrently. Together, these data enable 1) a picture of strain-specific and conserved metabolic responses during acute malaria, and 2) a comparison between metabolic responses and disease severity.

Results found

Linked to

	Label	Description
	SU001852 Subject (Entity type)	A subject produced as part of the PR001129 project
	SA164729 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164803 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164808 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164580 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164646 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164921 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164865 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164699 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project
	SA164581 Biosample (Entity type)	A biosample from Metabolomics produced as part of the PR001129 project

SU001852

Subject (Entity type)

A subject produced as part of the PR001129 project

SA164729

Biosample (Entity type)