Description:The Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative, is using several approaches to improve treatment for the millions of Americans who experience chronic pain, including that which affects joints. In particular, the Restoring Joint Health and Function to Reduce Pain (RE-JOIN) Consortium is using cutting-edge technology to expand our understanding of pain signaling in joints through a comprehensive characterization of sensory neurons (nerve cells) that allow us to feel pain. RE-JOIN scientists are focusing on two joints that often create chronic pain: the knee and the jaw, or temporomandibular (TMJ) joint.